Prostate cancer screening was discussed in the context of HIV at a presentation today by  L. Shepherd.

Her group showed some PSA difference perhaps in HIV positive men.

The study used conditional logistic regression models to investigate potential relationships between markers and prostate cancer. The suggestion from the study was that prostate cancer may occur at lower PSA levels in HIV positive men.

I found this suggestion remarkable given that the guidelines for the general population are so hotly debated. In this study there was no detail about how prostate cancer was defined.

It was not clear whether this was a true "screening" PSA process or whether these were symptomatic men.


This data will not change my view about PSA screening in all men positive or negative.